Prof. Dr. Manuel Mattheisen

Dr. Mattheisen is a physician by training, and has a strong background in genetic epidemiology, biostatistics and molecular and medical genetics. His work has led to identification and characterization of disease-causing genetic variation in a variety of disorders, including (but not limited to) bipolar disorder, obsessive-compulsive disorder (OCD), schizophrenia, substance use disorders, ADHD, autism, anxiety disorders, and major depressive disorder. As co-chair of the Psychiatric Genomics Consortium (PGC) TS/OCD disease working group and lead analyst for the PGC OCD and anxiety disorder GWAS his recent work has centered around (genetic) risk factors for bipolar disorder, OCD, depression and (specific) anxiety disorders. In addition, he is a member of the steering committee for the PGC and a council member for the Ancestral Populations Network, a NIMH funded network with the collective goal to accelerate genetic discovery for psychiatric disorders in cohorts of non-European ancestry and to advance the important goal of global mental health discovery and equity. He is co-PI on an EU funded grant for personalized treatment of bipolar disorder (ERA PerMed: PLOT-BD) and a NIMH funded grant to study OCD in Latin America (LATINO). Furthermore, he is subcontract PI on a NIMH funded project to study OCD in Scandinavian countries (NORDiC). He had the same role in a recently completed NIMH funded project on the same topic in Denmark (DOTS). Finally, he is co-PI on a CIHR funded large trans-national project on youth anxiety disorders (GAYA) that aims to characterize 13,000 participants with youth anxiety. He has co-authored more than 250 publications including publications in Lancet (2), Nature (6), Science (1), Cell (3), and Nature Genetics (25). He currently has a H-index of 70.

ORCID: 0000-0002-8442-493X

Web of Science ResearcherID: S-3725-2019