PARADISE study

Under the study motto "... countering anxiety, living more freely", the BMBF study "Jena-Paradies (Patient Activation foR Anxiety DIsordErS) investigated how a behavioural therapy anxiety exercise programme, supplemented by GP case management, helps the affected patients.

A practicable team approach makes full use of GP treatment options. The promising results of the three-year study are currently being published.

• Dreischulte T, Lukaschek K, Rottenkolber M, Werle J, Hiller TS, Breitbart J, Schumacher U, Brettschneider C, Margraf J, Gensichen J; PARADIES study group. Patient characteristics and changes in anxiety symptoms in patients with panic disorder: Post-hoc analysis of the PARADIES cluster randomised trial. PLoS One. 2022 Sep 29;17(9):e0275509. doi: 10.1371/journal.pone.0275509.
• Blank WA, Lukaschek K, Breitbart J, Hiller TS, Brettschneider C, Margraf J, Gensichen J; für die PARADIES-Studiengruppe. Perspektiven von Medizinischen Fachangestellten zu teambasierter Behandlung von Patienten mit Panikstörung in der Hausarztpraxis – Eine qualitative Studie [Health Assistants Perspectives on Team-Led Program for Patients with Panic Disorder in General Practice - A Qualitative Study]. Psychiatr Prax. 2021 Jul;48(5):258-264. German. doi: 10.1055/a-1310-2389. Epub 2020 Dec 3.
• Brettschneider C, Gensichen J, Hiller TS, Breitbart J, Schumacher U, Lukaschek K, Teismann T, Margraf J, König HH. Cost-effectiveness of Practice Team-Supported Exposure Training for Panic Disorder and Agoraphobia in Primary Care: a Cluster-Randomized Trial. J Gen Intern Med. 2020 Apr;35(4):1120-1126. doi: 10.1007/s11606-020-05658-9. Epub 2020 Jan 21.
  
• Lukaschek K, Hiller TS, Schumacher U, Teismann T, Breitbart J, Brettschneider C, König HH, Margraf J, Gensichen J. Symptom trajectories in patients with panic disorder in a primary care intervention: Results from a randomized controlled trial (PARADISE). Sci Rep. 2019 May 9;9(1):7170. doi: 10.1038/s41598-019-43487-x. 
  
• Brettschneider C, Bleibler F, Hiller TS, Konnopka A, Breitbart J, Margraf J, Gensichen J, König HH; Jena-PARADISE Study-Group. The allocation of resources in the care for patients with panic disorder in Germany: an excess cost analysis informing policy and science. Cost Eff Resour Alloc. 2019 Apr 27;17:9. doi: 10.1186/s12962-019-0177-4.
  
• Gensichen J, Hiller TS, Breitbart J, Brettschneider C, Teismann T, Schumacher U, Lukaschek K, Schelle M, Schneider N, Sommer M, Wensing M, König HH, Margraf J; Jena-PARADISE Study Group. Panic Disorder in Primary Care. Dtsch Arztebl Int. 2019 Mar 8;116(10):159-166. doi: 10.3238/arztebl.2019.0159.
  
• Teismann T, Lukaschek K, Hiller TS, Breitbart J, Brettschneider C, Schumacher U, Margraf J, Gensichen J; Jena Paradies Study Group. Suicidal ideation in primary care patients suffering from panic disorder with or without agoraphobia. BMC Psychiatry. 2018 Sep 24;18(1):305. doi: 10.1186/s12888-018-1894-5.
  
• Hiller TS, Freytag A, Breitbart J, Teismann T, Schöne E, Blank W, Schelle M, Vollmar HC, Margraf J, Gensichen J; für die Jena-PARADISE Study Group. Die Jena Angst-Monitoring-Liste (JAMoL) - ein Instrument zur evidenzbasierten Behandlung von Panikstörung mit oder ohne Agoraphobie in der Hausarztpraxis [The Jena Anxiety Monitoring List (JAMoL) - a tool for the evidence-based treatment of panic disorder with or without agoraphobia in primary care]. Z Evid Fortbild Qual Gesundhwes. 2018 Apr;131-132:28-37. German. doi: 10.1016/j.zefq.2018.02.003. Epub 2018 Mar 13.
  
• Sommer M, Hiller TS, Breitbart J, Schneider N, Teismann T, Freytag A, Gensichen J; für die „Jena-PARADISE“ Study Group. Standardtherapie für Panikstörung mit/ohne Agoraphobie in der Hausarztpraxis [Usual Care for Panic Disorder with/without Agoraphobia in Primary Care]. Psychiatr Prax. 2018 Apr;45(3):160-163. German. doi: 10.1055/s-0043-105058.