Institut für Allgemeinmedizin
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PARTNER study

Almost 9 million hospital admissions per year in Europe are attributed to adverse drug reactions (ADRs), about half of which are preventable. In Germany, too, 6.5% of all treatment cases in the emergency room were attributed to an ADR in a study at four large university hospitals.

The risk is increased especially in older patients (65+) with multi-medication (simultaneous intake of ≥ 5 drugs). In these patients, ADRs can have serious consequences that not only lead to acute events but also have a lasting impact on quality of life. Particularly relevant in this context are falls with fractures, cognitive impairment including delirium, cardiac arrhythmias and gastrointestinal complaints such as ulcers, bleeding and constipation.

To prevent avoidable ADRs, guidelines recommend regular medication analysis, which in many cases is complemented by structured medication management to promote patient compliance and to observe the effects of medication changes and to be able to react to them promptly if necessary. In medication analysis and medication management, the PARTNER study relies on intensified and coordinated cooperation between GPs and pharmacists.