SMOOTH study
Structured long-term care for patients after sepsis
[DRKS-ID: DRKS00000741]
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The BMBF study developed and investigated a GP follow-up programme for patients after severe sepsis. For this purpose, the patients were actively followed up by their family doctor after discharge from hospital.
The intervention group of a total of 291 patients in 148 GP practices showed an improvement in motor function. The Smooth study (Sepsis survivors Monitoring and cOordination in OutpatienT Healthcare) drew international attention to the long-term consequences of sepsis. It showed the first approaches to improving treatment for these patients in GP practices and was published in JAMA in 2016.
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- Kosilek RP, Schmidt K, Baumeister SE, Gensichen J; SMOOTH Study Group. Frequency and risk factors of post-intensive care syndrome components in a multicenter randomized controlled trial of German sepsis survivors. J Crit Care. 2021 Oct;65:268-273. doi: 10.1016/j.jcrc.2021.07.006.
- Gehrke-Beck S, Gensichen J, Turner KM, Heintze C, Schmidt KF; SMOOTH Study Group. General practitioners' views and experiences in caring for patients after sepsis: a qualitative interview study. BMJ Open. 2021 Feb 10;11(2):e040533. doi: 10.1136/bmjopen-2020-040533.
- Schmidt KF, Schwarzkopf D, Baldwin LM, Brunkhorst FM, Freytag A, Heintze C, Reinhart K, Schneider N, von Korff M, Worrack S, Wensing M, Gensichen J; SMOOTH Study Group. Long-Term Courses of Sepsis Survivors: Effects of a Primary Care Management Intervention. Am J Med. 2020 Mar;133(3):381-385.e5. doi: 10.1016/j.amjmed.2019.08.033. Epub 2019 Sep 13. PMID: 31521666.
- Schmidt K, Worrack S, Von Korff M, Davydow D, Brunkhorst F, Ehlert U, Pausch C, Mehlhorn J, Schneider N, Scherag A, Freytag A, Reinhart K, Wensing M, Gensichen J; SMOOTH Study Group. Effect of a Primary Care Management Intervention on Mental Health-Related Quality of Life Among Survivors of Sepsis: A Randomized Clinical Trial. JAMA. 2016 Jun 28;315(24):2703-11. doi: 10.1001/jama.2016.7207.
- Schmidt K, Mühlberg J, Brunkhorst FM, Gensichen J. Die Betreuung des Intensivpatienten ist mit der Entlassung nicht zu Ende: Post-ICU-Care. Intensiv-News. 2016(1):26-8.
- Schmidt K, Thiel P, Mueller F, Schmuecker K, Worrack S, Mehlhorn J, Engel C, Brenk-Franz K, Kausche S, Jakobi U, Bindara-Klippel A, Schneider N, Freytag A, Davydow D, Wensing M, Brunkhorst FM, Gensichen J; Smooth Study Group. Sepsis survivors monitoring and coordination in outpatient health care (SMOOTH): study protocol for a randomized controlled trial. Trials. 2014 Jul 11;15:283. doi: 10.1186/1745-6215-15-283.
- Mehlhorn J, Freytag A, Schmidt K, Brunkhorst FM, Graf J, Troitzsch U, Schlattmann P, Wensing M, Gensichen J. Rehabilitation interventions for postintensive care syndrome: a systematic review. Crit Care Med. 2014 May;42(5):1263-71. doi: 10.1097/CCM.0000000000000148.
