Literaturverzeichnis und Publikationen
Hier können Sie Einblicke und Eindrücke in die Veröffentlichungen unserer Mediziner und Wissenschaftler gewinnen und sich über unser Wirken in den letzten 5 Jahren weiter Informieren.
2024
- Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes
- Preoperative Midazolam and Patient-Centered Outcomes of Older Patients: The I-PROMOTE Randomized Clinical Trial
- Prosaposin hyperglycosylation: a novel tumor immune escape mechanism and implications for cancer immunotherapy
- Blockade of the CD47/SIRPα checkpoint axis potentiates the macrophage-mediated anti-tumor efficacy of tafasitamab
- Enhanced potency of immunotherapy against B-cell precursor acute lymphoblastic leukemia by combination of an Fc-engineered CD19 antibody and CD47 blockade
- Efficient Chimeric Antigen Receptor T-Cell Generation Starting with Leukoreduction System Chambers of Thrombocyte Apheresis Sets
2023
- Purified recombinant lentiviral Vpx proteins maintain their SAMHD1 degradation efficiency in resting CD4+ T cells
- Defined Human Leukemic CD34+ Liquid Cultures to Study HDAC/Transcriptional Repressor Complexes
- Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia
- The prevalence of sepsis-induced coagulopathy in patients with sepsis - a secondary analysis of two German multicenter randomized controlled trials
- Predictive value of molecular matching tools for the development of donor specific HLA-antibodies in patients undergoing lung transplantation
- Monitoring Blood Supply in Germany: A Regulatory Perspective
- Principles of Therapeutic Apheresis in Neurological Disease
- Emicizumab for the Treatment of Acquired Hemophilia A: Consensus Recommendations from the GTH-AHA Working Group
- Emicizumab prophylaxis in patients with acquired haemophilia A (GTH-AHA-EMI): an open-label, single-arm, multicentre, phase 2 study
- [Basics for the Use of Andexanet]
- Predictive value of molecular matching tools for the development of donor specific HLA-antibodies in patients undergoing lung transplantation
- Novel NKG2D-directed bispecific antibodies enhance antibody-mediated killing of malignant B cells by NK cells and T cells
- Perspectives of targeting LILRB1 in innate and adaptive immune checkpoint therapy of cancer
2022
- Head and neck tumor cells treated with hypofractionated irradiation die via apoptosis and are better taken up by M1-like macrophages
- Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages
- ATMPs: New Challenge for Transfusion Services
- Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses
- Defined Human Leukemic CD34+ Liquid Cultures to Study HDAC/Transcriptional Repressor Complexes
- Understanding opalescence measurements of biologics - A comparison study of methods, standards, and molecules
- [Autoimmune haemolytic anemias]
- Specific effects of somatic GATA2 zinc finger mutations on erythroid differentiation
- Receiving, Handling, Storage, Thawing, Distribution, and Administration of CAR-T Cells Shipped from the Manufacturing Facility
- Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody
- Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab
- Immunotherapeutic targeting of activating natural killer cell receptors and their ligands in cancer
- The Novel Dual Topoisomerase Inhibitor P8-D6 Shows Anti-myeloma Activity In Vitro and In Vivo
- Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection
- HLA-DRB1∗16 and -DQB1∗05 alleles are strongly associated with autoimmune pancreatitis in a cohort of hundred patients
- Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection
- Corticotropin-stimulated steroid profiles to predict shock development and mortality in sepsis: From the HYPRESS study
- Ecological effects of selective oral decontamination on multidrug-resistance bacteria acquired in the intensive care unit: a case-control study over 5 years
- [Update of the Surviving Sepsis Campaign guidelines 2021-What is new?]
- [Practice of pharmaceutical thrombosis prophylaxis and anticoagulation in patients with sepsis and pre-existing anticoagulation or heparin-induced type II thrombocytopenia-Results of a nationwide survey in German intensive care units]
- A novel approach to laboratory assessment and reporting of platelet von Willebrand factor
- [SEPSIS-3.0-Is intensive care medicine ready for ICD-11?]
- [Erratum to: Treatment of sepsis-induced coagulopathy. Results of a Germany-wide survey in intensive care units]
- [Anticoagulation in intensive care medicine]
- Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL
- Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies by augmenting tumor cell phagocytosis
2021
- Tumor cell lysis and synergistically enhanced antibody-dependent cell-mediated cytotoxicity by NKG2D engagement with a bispecific immunoligand targeting the HER2 antigen
- Emergency Use of Convalescent Plasma: Perception of the Regulatory Framework from a Clinical Perspective
- SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells
- Enhancement of epidermal growth factor receptor antibody tumor immunotherapy by glutaminyl cyclase inhibition to interfere with CD47/signal regulatory protein alpha interactions
- [Update 2021: COVID-19 from the Perspective of Haematology and Haemostaseology]
- Reduction of RUNX1 transcription factor activity by a CBFA2T3-mimicking peptide: application to B cell precursor acute lymphoblastic leukemia
- The selection of variable regions affects effector mechanisms of IgA antibodies against CD20
- Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy
- Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo
- Association of CMV-specific T-cell immunity and risk of CMV infection in lung transplant recipients
- [Treatment of sepsis-induced coagulopathy : Results of a Germany-wide survey in intensive care units]
- Persistent inhibitor in acquired haemophilia A: A case for emicizumab?
2020
- Ischemic stroke and dose adjustment of oral Factor Xa inhibitors in patients with atrial fibrillation
- Epigenetic Compound Screening Uncovers Small Molecules for Reactivation of Latent HIV-1
- Enhancing CDC and ADCC of CD19 Antibodies by Combining Fc Protein-Engineering with Fc Glyco-Engineering
- The global scale, distribution and growth of aviation: Implications for climate change
- [COVID-19 from the Perspective of Haematology and Haemostaseology]
- Impact, Screening, and Therapy of HLA Antibodies in Patients before and after Lung Transplantation
- ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells
- Early conversion to a CNI-free immunosuppression with SRL after renal transplantation-Long-term follow-up of a multicenter trial
- Dynamic changes in circulating T follicular helper cell composition predict neutralising antibody responses after yellow fever vaccination
- Comparison of Two Different Fibrinogen Concentrates in an in vitro Model of Dilutional Coagulopathy
2019
- Direct Oral Anticoagulant Plasma Levels for the Management of Acute Ischemic Stroke
- Closing the gap - detection of clinically relevant von Willebrand disease in emergency settings through an improved algorithm based on rotational Thromboelastometry
- Data mining of reference intervals for coagulation screening tests in adult patients
- Oncogenic Deregulation of Cell Adhesion Molecules in Leukemia
- Chimeric Antigen Receptor T Cells: A Race to Revolutionize Cancer Therapy
- Cellular Therapeutics - Living Drugs: A Rising Star at the Horizon of Immunotherapy in Hematology and Oncology
- Oncogenic Deregulation of Cell Adhesion Molecules in Leukemia
- Compatibility of RUNX1/ETO fusion protein modules driving CD34+ human progenitor cell expansion
- Daratumumab eradicates minimal residual disease in a preclinical model of pediatric T-cell acute lymphoblastic leukemia
- Targeted in-vitro-stimulation reveals highly proliferative multi-virus-specific human central memory T cells as candidates for prophylactic T cell therapy
- Perioperative Management of a Patient with Severe Factor V Deficiency Presenting with Chronic Subdural Hematoma: A Clinical Report
- Emicizumab in the Treatment of Acquired Haemophilia: A Case Report