Pathophysiology of Primary Aldosteronism (AG Williams)

AG Williams investigates the physiology and pathophysiology of the adrenal cortex with a specific interest in primary aldosteronism. Tracy´s currently funded projects as principal investigator include:

• Molecular mechanisms of tumorigenesis in primary aldosteronism

• Pathophysiology and advanced approaches for subtyping in primary aldosteronism

• The physiology and pathophysiology of porcine aldosterone production.

The team has multiple and diverse projects ranging from the pathophysiology of primary aldosteronism using molecular histopathology and spatial and single cell omics technologies to clinical investigations for the identification of predictors of therapeutic responses to primary aldosteronism-specific therapies.

Before joining Munich, Tracy was responsible for a Molecular Biology laboratory in the Department of Medical Sciences, University of Turin, Italy, after obtaining an EMBO long-term fellowship and a Marie-Curie research training grant. Prior to this, she spent several years at the Collège de France, Paris, France, as a postdoctoral fellow focussing on the molecular biology of angiotensin-I converting enzyme. Tracy earned her PhD and BSc degrees from the Department of Biochemistry and Molecular Biology at the University of Leeds, UK and was awarded a fellowship from the Royal Society of Great Britain.

Since 2022: Member of the Endocrine Society Primary Aldosteronism Guideline development panel

Since 2018: Editorial board member of Hypertension

2015 to 2019: ENS@T executive committee member

PI/Group leader: Tracy Williams PhD

• Postdoctoral fellow: Zhuolun Sun MD PhD

• PhD student: Siyuan Gong MD

• PhD student: Sanas Mir-Bashiri MSc

• PhD student: Yingxian Pang MD

• PhD student: Jia Wei MD

• Technical assistant: Petra Rank

• Technical assistant: Youssra Mohammed

• Technical assistant: Beate Heuser

• Technical assistant: Carolin Ellerbrock